Krista Holmstrom
The lymphatic system, consisting of lymph vessels, ducts, nodes and tissues organized throughout the body, serves to regulate fluid homeostasis, defend against disease, and aid in the absorption of nutrients. To maintain a healthy environment, lymphatic endothelial cells continuously adapt and respond to mechanical changes arising from disease and immune response. Through this investigation, Human Dermal Lymphatic Endothelial Cells (HDLECs) were tested against shear stress from flowing media to test maintenance of their lymphatic phenotype.