Phuong-Uyen Tran-Dinh
Per- and polyfluoroalkyl substances (PFAS) are bioaccumulative synthetic compounds of high risk to ecosystems and human health. Their persistence against biodegradation is attributed to the strength of the carbon–fluorine (C–F) bonds, which are rarely cleaved under natural conditions. While enzymatic approaches have been explored as more sustainable alternatives to traditional remediation methods, enzymes capable of transforming fluorinated compounds with broad substrate specificity remain scarce.