Serotonin is the key hormone in stabilizing our mood and feelings of well-being. The relation between alterations in the levels of serotonin in the central nervous system and depression has been well-established. The most common antidepressants prescribed to alleviate the symptoms of depression are selective serotonin reuptake inhibitors (SSRIs), which increase the levels of serotonin in the brain.
It is well established that many species of fish avoid carbon dioxide (CO2) enriched waters. However, carbon dioxide is known to create carbonic acid when it dissolves, so it is possible that either the gas itself and/or the acidity of the carbonic acid (pH) could be responsible. Notably, some fish have external taste systems that can detect both dissolved CO2 and pH. Because CO2 has been suggested for use as an invasive species deterrent, it is important to understand the basis of this response.
Amyloid fibrils are large multimeric assemblies that have been found to accumulate in several brain regions of patients suffering from Parkinson’s, Multiple Systems Atrophy, Alzheimer’s, Chronic Traumatic Encephalopathy, Prion, and other neurological diseases. These assemblies have been found to be toxic in vivo and in vitro and correlate with the progression of their associated diseases. The recent development of cryo-EM technology resulted in the publication of over 100 different fibril structures.
Amyloid fibrils are large multimeric assemblies that have been found to accumulate in several brain regions of patients suffering from Parkinson’s, Multiple Systems Atrophy, Alzheimer’s, Chronic Traumatic Encephalopathy, Prion, and other neurological diseases. These assemblies have been found to be toxic in vivo and in vitro and correlate with the progression of their associated diseases. The recent development of cryo-EM technology resulted in the publication of over 100 different fibril structures.
Cortico-striatal circuits are central to several cognitive processes, including cognitive control: the ability to regulate and refrain from a learned behavior to achieve a specific goal. Deficits in this process are common in obsessive-compulsive disorder, major depression, and many other psychiatric disorders. Compulsive behaviors are one such deficit in which actions are performed persistently and repetitively without necessarily leading to rewards or goals.
The peptide molecule oxytocin has been implicated in regulating a range of bodily functions from lactation and arousal, with more recent ties to social behavior. Though relatively uncommon within mammal species, a mode of social behavior exists known as pair bonding, which has been characterized as strong social or sexual attachment between two members of a species, and has been shown to be reinforced through neural interactions with oxytocin.
The circadian clock is a ~24-hour endogenous timekeeper conserved across kingdoms. The cyclic expression of CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) is an important component of the Arabidopsis thaliana circadian clock. Although light signaling is the main stimulus which regulates CCA1 expression, other factors such as temperature and phytohormone exposure can change the expression pattern of this gene to alter clock parameters. Brassinosteroids are a class of phytohormones that play a crucial role in plant growth and development and have been shown to inhibit the expression of CCA1.
Parkinson’s Disease (PD) is expected to affect more than one million people in the United States by the year 2030, highlighting the growing need for more precise tools for measuring and monitoring symptom progression for the purpose of better patient-specific treatment, and care options for those affected. The clinical pull test is used to determine the progression of balance impairment during disease progression, but is limited by its inconsistency of perturbation. Additionally, its use of coarse rating causes difficulty when measuring fine differences in balance impairment.
Stress and mental health is a common occurrence for college students, especially those in the student-athlete population. With a greater prevalence of women reporting struggles with mental health, there is a gap in literature identifying the further implication that racialized identity could have. Lower levels of self-efficacy and higher levels of stress could have an impact on student-athletes well-being and performance. PURPOSE: To explore potential differences in self-efficacy and perceived stress in Division-1 female athletes by race.
Within contexts of healthcare and human computer interaction, behavioral nudging has primarily been defined as a mechanism to alter a person’s behavior in a predictable way to promote self-reflection and awareness about healthier behaviors. This notion of nudging is derived from an understanding of cognitive biases, such as heuristics and taking the path of least resistance. However, most previous technology mediated nudging tools in this context have failed to emphasize accessibility and current design considerations don’t protect user autonomy.